Description KPV (Lys-Pro-Val) is a naturally occurring tripeptide fragment derived from the alpha-melanocyte-stimulating hormone (α-MSH). It is studied for its potent anti-inflammatory, antimicrobial, and wound-healing properties, with a strong safety profile observed in preclinical models. Product Highlights Each vial contains 10 mL solution (~100 sprays) Each spray delivers 0.1 mL = 100 mcg KPV Total KPV Content: 10 mg per vial Specialized pharmaceutical-grade nasal solution — designed for comfort and ease on the nose Unlike many other nasal sprays on the market, this formula avoids irritation and dryness Packaged in Class A, lead-free pharmaceutical glass bottles Tamper/Child-Proof Cap Orifice Reducer for integrity, sterility, and ease of use Description KPV is a bioactive tripeptide known for its anti-inflammatory and immunomodulatory effects. It is studied for its ability to inhibit pro-inflammatory cytokines, protect epithelial barriers, and promote healing in models of inflammation, infection, and tissue injury. Benefits Anti-inflammatory — studied for reducing inflammatory cytokine expression (e.g., TNF-α, IL-1β, IL-6) Wound healing — explored for accelerating epithelial repair and collagen synthesis Antimicrobial — shows activity against bacterial and fungal pathogens in preclinical studies Barrier protection — supports gut, skin, and mucosal integrity under stress conditions Safe and stable — exhibits strong safety profile and stability in various formulations Localized Effects with Nasal Spray Rapid uptake through the nasal mucosa Direct action on inflammatory and immune-modulating pathways Formulated with a specialized isotonic nasal vehicle to minimize irritation and dryness What Researchers Use It For Research in inflammatory bowel disease, dermatitis, and mucosal inflammation models Studies on antimicrobial and epithelial barrier protection mechanisms Exploration of melanocortin receptor modulation in immune signaling Tissue healing and repair under oxidative or inflammatory stress conditions Identity & Specs Sequence: Lys-Pro-Val Formula / M.W.: C17H31N5O4, ~369.47 g/mol CAS: 72682-81-4 Form: Sterile nasal spray solution Net per vial: 10 mL (~100 sprays) Total Content: 10 mg KPV per vial Purity: ≥99% (HPLC) Identity: MS-verified (per COA) Storage: Refrigerate 2–8 °C, protect from light Selected Research PubChem entry — chemical identity: https://pubchem.ncbi.nlm.nih.gov/compound/9940460 Anti-inflammatory mechanisms of KPV: https://pubmed.ncbi.nlm.nih.gov/21763249/ Barrier protection and epithelial repair: https://pubmed.ncbi.nlm.nih.gov/24316118/ Melanocortin receptor and immune signaling studies: https://pubmed.ncbi.nlm.nih.gov/21925274/ Antimicrobial peptide activity review: https://pubmed.ncbi.nlm.nih.gov/25596211/ ⚠️ Disclaimer This product is intended for laboratory research use only. Not for human or veterinary use. Not approved for diagnostic, therapeutic, or medical applications. Handle using appropriate laboratory safety procedures and personal protective equipment.
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